Indy Gastro | Colonoscopy, rectal bleeding, diarrhea, constipation, endoscopy

Brian G. Sperl, MD



Gary, Indiana native Dr. Brian G. Sperl is a member of the Board of Managers at the Mooresville Endoscopy Center and a past Treasurer of Indianapolis Gastroenterology and Hepatology.  




Dr. Sperl enjoys a special interest in inflammatory bowel disease (IBD) specifically ulcerative colitis and Crohn’s disease.  He also performs ablation of dysplastic Barrett’s esophagus.   

Graduating with High Distinction from Indiana University in 1979, he enrolled in the Indiana University School of Medicine.  He completed his Internal Medicine Internship and Residency at Methodist Hospital of Indianapolis in 1986 where he served as the Chief Resident of Transitional Care that year.  Dr. Sperl completed his Gastroenterology Fellowship at the University of Louisville in Kentucky in 1988.  In 2012, he was recognized by Indianapolis Monthly Magazine as one of the region's Top Doctors.

Dr. Sperl is a member of the Indianapolis Medical Society, the American College of Gastroenterology and the Indiana State Medical Association.  He enjoys hiking and photography in America’s National Parks. 




Graduated with High Distinction

Indiana University

Top Doctors 




Education & Training

Indiana University in 1979

Medical Degree from the Indiana University School of Medicine in 1983

Internal Medicine Internship at Methodist Hospital in 1984

Internal Medicine Residency at Methodist Hospital in 1986

Chief Resident of Transitional Medicine, Methodist Hospital


Gastroenterology Fellowship at the University of Louisville in 1988




Board Certifications


Patient Reviews

Sperl was very thorough as usual. He explained exactly what he was doing and why. I appreciate him so much!  Luann was so very kind when I was checking out. Giving me her direct phone number. So nice!!!!  Judy took my blood and hit my vein the very first time.



Dr Sperl has been my doctor for several years and I think he is wonderful. He is always professional, friendly and takes whatever time I need to discuss my medical issues. Dr. Sperl is very good at explaining things to me and making sure I understand. He never sugesting medicine or tests that he does not feel in 100% needed. I have recommeneded Dr Sperl to friends and will continue to do so. Also, the nurses/assistants have always been pleasent and professional as well. I trust Dr Sperl with my life.



Dr. Sperl is a great asset to the Indy Gastro Team.

Being a nurse myself, at times we can be the more challenging patient. However the repor I have developed with Dr. Sperl is fantastic and he he a great professional. I woudl recommend him highly. I am always seen in a prompt manner and he is very attentive and understanding. I thank God he was put on my service in the hospital.

Thank You Indy Gastro!



I always receive exceptional care when I am in the office. Dr Sperl and his staff are wonderful.



I've been a patient for 14 years, and have followed Dr. Sperl when he moved from one practice to another since I refuse to give him up. I moved away but willingly drive 1 1/2 hours so that I can still see him. He is an extremely compassionate and caring person who seems to care about the whole me, and not just about my intestines. He's the only doctor I've ever been to that cares that I have a life outside his office. He always asks about my kids and my job.

He gives me praise when things are going great in my life, gives support when things aren't so great, and tolerates my frustrations when I'm tired of having Crohn's. He listens to my input about my disease and makes me feel that he and I are in a partnership. He takes my thoughts into consideration and fully discusses the various options with me so that WE can decide upon the best course of action. Dr. Sperl understands how frustrating it is to have a disease. He's helped me know that I will survive this thing!



Nothing to add. All personel were professional and showed courtesy. Dr. Sperl explained procedure before surgery. The worst part about this is and always will be the day before the procedure.



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    8051 S. Emerson Ave.
    Suites 150 & 200
    Indianapolis, IN 46237

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